OCD affects approximately 2.5 million U.S. adults, or 1.2% of the population, according to the ADAA
OCD Treatment in La Crosse, WI: When the Loop Won't Stop
IV ketamine therapy and Spravato offer a neurologically distinct approach for people with OCD that hasn't responded to conventional treatment. Medically supervised, personalized care in La Crosse, backed by emerging clinical evidence.
OCD Is One of the Most Disabling Mental Health Conditions. Standard Treatments Don't Work for Everyone.
OCD affects approximately 2.5 million U.S. adults, and for many of them, first-line treatments like SSRIs and cognitive behavioral therapy with exposure and response prevention (ERP) provide meaningful but incomplete relief. When the intrusive thoughts keep cycling and the compulsions keep pulling despite your best efforts, it’s exhausting in a way that’s hard to describe to someone who hasn’t lived it.
At Relevate Ketafusion, we offer IV ketamine therapy and Spravato for people with OCD and OCD-related conditions that haven’t responded adequately to conventional approaches. The research on ketamine for OCD is still developing, but early clinical evidence is promising, and the neurological mechanism, interrupting the entrenched neural loops that drive obsessive thinking, makes compelling scientific sense.
We’ll always be honest with you about what the research shows. What we can tell you is that for patients with treatment-resistant OCD, ketamine therapy offers a genuinely different path worth exploring.


Understanding OCD: Stuck in a Loop the Brain Won't Release
OCD is characterized by two core features: obsessions, which are unwanted, intrusive thoughts, images, or urges that trigger significant distress, and compulsions, which are repetitive behaviors or mental acts performed to neutralize that distress. The relief from compulsions is temporary. The obsessions return. The loop reinforces itself, often becoming more entrenched over time.
Neurologically, OCD involves dysregulation in the cortico-striato-thalamo-cortical circuits, the feedback loops that connect the prefrontal cortex with deeper brain structures involved in habit formation and threat detection. These circuits get stuck in a pattern of excessive signaling that conventional SSRIs can dampen but often can’t fully break. That’s where ketamine’s mechanism becomes relevant: by acting on glutamate and NMDA receptors rather than serotonin, it targets a different part of the neurological machinery driving OCD.
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OCD and Related Conditions We Treat
OCD takes many forms, and the intrusive thoughts and compulsive behaviors that define it can focus on a wide range of themes. Ketamine therapy's potential to interrupt entrenched neural loops is relevant across these presentations, particularly when combined with ongoing behavioral therapy.
Treatment-Resistant OCD
When SSRIs at adequate doses and multiple rounds of ERP therapy haven't produced sufficient relief, treatment-resistant OCD is the clinical reality. Early studies examining ketamine for OCD found that a single IV ketamine infusion produced significant symptom reduction in a majority of patients at four weeks post-infusion, with improvements observed rapidly after treatment. For a condition where response to conventional medication can take months to assess, that speed is meaningful.
OCD with Co-Occurring Depression
Depression is one of the most common co-occurring conditions in people with OCD, and the two can create a deeply discouraging cycle: OCD symptoms worsen mood, and low mood reduces the capacity to resist compulsions. Ketamine therapy addresses both simultaneously, which is a significant advantage over treatments that target only one condition at a time. Spravato carries an FDA approval for treatment-resistant depression that makes it a well-validated option for this overlap.
OCD with Anxiety
Anxiety is the engine that drives OCD. The intrusive thought triggers anxiety, the compulsion temporarily relieves it, and the cycle continues. Ketamine's ability to calm overactive neural circuits, including those driving anxious threat responses, can help reduce the urgency of the obsessive-compulsive loop and create space for behavioral therapeutic work to take hold more effectively.
OCD with Suicidal Ideation
The relentless nature of severe OCD can lead to profound hopelessness and, in some cases, suicidal thoughts. When this is part of the picture, waiting weeks for a medication to build up isn't acceptable. Spravato's FDA approval for MDD with active suicidal ideation makes it a specifically indicated, fast-acting option for patients whose OCD-related suffering has reached this level of severity.
Body Dysmorphic Disorder (BDD)
BDD shares the same underlying neurological profile as OCD, with intrusive, distressing preoccupations and repetitive behaviors aimed at managing them. Emerging research suggests ketamine's mechanism may be relevant for BDD as it is for OCD, particularly in patients who haven't responded to SSRIs. Our team will evaluate your full clinical picture and help determine whether ketamine therapy is an appropriate option.
Your OCD Treatment Journey at Relevate Ketafusion
From your first conversation to your last session, we're with you at every step.
01
Initial Consultation
Your journey starts with a virtual consultation. We'll talk through your OCD history, your current symptoms, the treatments you've tried, and what you're hoping to achieve. We'll be direct about what ketamine therapy can and can't offer for OCD based on current evidence, and we'll help you decide whether it's worth pursuing as part of your overall treatment approach. No commitment required.
02
Personalized Treatment Plan
We build your plan around your specific diagnosis, history, and goals. For OCD patients, we'll also discuss how ketamine therapy fits alongside any ongoing behavioral therapy you're receiving, since the evidence suggests the combination of ketamine and exposure-based CBT produces better outcomes than either alone. We'll map out your full timeline and set clear expectations from the start.
03
Treatment Sessions
Every session takes place in a private, calm treatment room with ambient lighting and soothing music. Our medical team stays present throughout, monitoring your vitals and your comfort in real time. Most patients describe the experience as peaceful. Plan to have someone drive you home afterward.
04
Integration and Ongoing Monitoring
We track your response carefully and adjust your plan as needed. The period following ketamine sessions is when the brain's increased neuroplasticity makes behavioral therapeutic work particularly effective, so we'll discuss how to make the most of that window. After your initial series, we'll develop a maintenance approach that fits your life and your ongoing treatment.
Our OCD Treatments: IV Ketamine and Spravato
We offer two clinically validated, rapid-acting treatments that show promise for OCD and related conditions. Your provider will help determine the right fit based on your diagnosis, history, and goals.
IV Ketamine Therapy for Neuropathic Pain
Administered directly into the bloodstream through a small IV line, ketamine infusions offer precise dosing and rapid effect. Sessions typically last 40 to 60 minutes in a private, calm treatment room. Early clinical research published in the Journal of Clinical Psychiatry found significant OCD symptom reduction at four weeks post-infusion in the majority of patients who received a single IV ketamine infusion alongside exposure-based CBT. IV ketamine is a self-pay treatment and not covered by insurance.
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Spravato (Esketamine) Therapy
FDA-approved for treatment-resistant depression and MDD with suicidal ideation, Spravato works on the same glutamate pathway as IV ketamine and offers a well-validated option for patients whose OCD co-occurs with treatment-resistant depression. You self-administer the nasal spray in our clinic under direct medical supervision, followed by a required monitoring period of approximately two hours. Spravato is covered by most major insurance plans.
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The Science Behind Ketamine for OCD
The current gold standard for OCD, SSRIs combined with ERP therapy, works by adjusting serotonin levels and through behavioral extinction of compulsive responses. For a meaningful portion of patients, this isn’t enough. Ketamine takes a different neurological route that’s generating serious scientific interest.
OCD involves dysfunction in cortico-striato-thalamo-cortical circuits, the feedback loops that regulate habitual and threat-driven behaviors. These loops involve glutamate signaling. Ketamine blocks NMDA receptors and directly modulates glutamate activity, potentially interrupting the excessive signaling that keeps OCD loops running. It also promotes rapid neuroplasticity, which may help the brain form new, healthier patterns of response to intrusive thoughts.
The research is still developing, and we want to be transparent about that. But what exists is genuinely promising, and the neurological rationale is sound.

Why Choose Relevate Ketafusion for OCD Treatment
01
Honest About What the Evidence Shows
We won’t oversell ketamine for OCD. The research is promising but still developing, and we’ll tell you that directly. What we will do is give you a thorough, honest evaluation of whether ketamine therapy is a reasonable option for your specific situation, and help you make an informed decision with full context.
02
The Only IV Ketamine Clinic in the Coulee Region
Relevate Ketafusion is the only provider in the La Crosse area offering IV ketamine infusions. The nearest alternative is over two hours away. If you’re going to explore ketamine therapy for OCD, you shouldn’t have to travel hours to do it.
03
Spravato Covered by Insurance
For patients whose OCD co-occurs with treatment-resistant depression, Spravato is covered by most major insurance plans. Our team verifies your coverage before your first session and handles prior authorization. For IV ketamine, transparent self-pay pricing is available with HSA/FSA acceptance and CareCredit financing.
04
A Medical Team With Deep Psychiatric Expertise
Dr. Howard Schumaker’s dual board certifications and chemical engineering background mean he understands ketamine’s mechanism at a level most clinicians don’t. Our nurse practitioners hold dual FNP and PMHNP certifications, bringing both family medicine and psychiatric expertise to every patient they work with.
05
Continuous Medical Supervision at Every Session
Every session happens under direct medical supervision with continuous monitoring. You’re never alone, and our team responds in real time throughout every visit. Safety and attentiveness are non-negotiable at Relevate.
06
Founded by Someone Who Knows What It Means to Keep Searching
Tina Schumaker built Relevate after her own experience with treatment-resistant depression and PTSD. She knows what it feels like to have tried what’s available and still not feel better. That experience is woven into how this clinic operates, and it shows in the care every patient receives.
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